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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K8 All Species: 30.91
Human Site: Y445 Identified Species: 97.14
UniProt: P41279 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41279 NP_005195.2 467 52925 Y445 L K R Q R S L Y I D L G A L A
Chimpanzee Pan troglodytes XP_001136851 572 63619 Y550 L K R Q R S L Y I D L G A L A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544213 704 77443 Y682 L K R Q R S L Y I D L G A L A
Cat Felis silvestris
Mouse Mus musculus Q07174 467 52923 Y445 L R R Q R S L Y I D L G A L A
Rat Rattus norvegicus Q63562 467 52789 Y445 L R R Q R S L Y I D L G A L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507627 553 62220 Y531 L K R Q R S L Y I D L G A L A
Chicken Gallus gallus XP_418581 468 53236 Y446 V K R Q R S L Y I D L G A L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692177 461 52316 Y439 S K K K G S L Y I D L G A F A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.2 N.A. 64.4 N.A. 93.3 94 N.A. 76.6 83.7 N.A. 60.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 81.4 N.A. 65.3 N.A. 97.4 97.2 N.A. 80.4 92.9 N.A. 73.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 100 93.3 N.A. 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 N.A. 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 100 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % F
% Gly: 0 0 0 0 13 0 0 0 0 0 0 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % I
% Lys: 0 75 13 13 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 75 0 0 0 0 0 100 0 0 0 100 0 0 88 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 88 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 25 88 0 88 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _